Left Mouse Button: Interact with villagers and objects.
Space Bar (Hold): Initiate Gesture Casting for spells.
Number Keys (1-8): Hotkeys for the cooresponding spell slots on your spell toolbar.
Cursor Keys Up and Down (or "W" and "S"): Move the object you are holding back and forth in depth (Optional).
"P" key, Escape, or Pause/Break: Pause the game. Also allows access to the options screen.